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Multispectral LEDs Eliminate Lipofuscin-Associated Autofluorescence for Immunohistochemistry and CD44 Variant Detection by in Situ Hybridization in Aging Human, non-Human Primate, and Murine Brain

A major limitation of mechanistic studies in aging brains is the lack of routine methods to robustly visualize and discriminate the cellular distribution of tissue antigens using fluorescent immunohistochemical multi-labeling techniques. Although such approaches are routine in non-aging brains, they...

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Detalles Bibliográficos
Autores principales: Adeniyi, Philip A., Fopiano, Katie-Anne, Banine, Fatima, Garcia, Mariel, Gong, Xi, Keene, C. Dirk, Sherman, Larry S., Bagi, Zsolt, Back, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520168/
https://www.ncbi.nlm.nih.gov/pubmed/36164936
http://dx.doi.org/10.1177/17590914221123138