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Microbiome-Related Indole and Serotonin Metabolites are Linked to Inflammation and Psychiatric Symptoms in People Living with HIV

BACKGROUND: People living with HIV (PLHIV) exhibit dysregulation of tryptophan metabolism. Altered gut microbiome composition in PLHIV might be involved. Mechanistic consequences within the 3 major tryptophan metabolism pathways (serotonin, kynurenine, and indoles), and functional consequences for p...

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Detalles Bibliográficos
Autores principales: Vadaq, Nadira, Zhang, Yue, Meeder, Elise, Van de Wijer, Lisa, Gasem, Muhammad Hussein, Joosten, Leo AB, Netea, Mihai G, de Mast, Quirijn, Matzaraki, Vasiliki, Schellekens, Arnt, Fu, Jingyuan, van der Ven, André JAM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520182/
https://www.ncbi.nlm.nih.gov/pubmed/36187510
http://dx.doi.org/10.1177/11786469221126888