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Systematic evaluation of irinotecan-induced intestinal mucositis based on metabolomics analysis

Chemotherapy-induced intestinal mucositis (CIM) is a major dose-limiting side effect of chemotherapy, especially in regimens containing irinotecan (CPT-11). Several studies on the pathologic mechanisms of CIM focused on both the genomics and molecular pathways triggered by chemotherapy. However, sys...

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Detalles Bibliográficos
Autores principales: Yu, Qing-Qing, Zhang, Heng, Zhao, Shiyuan, Xie, Dadi, Zhao, Haibo, Chen, Weidong, Pang, Min, Han, Baoqin, Jiang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520243/
https://www.ncbi.nlm.nih.gov/pubmed/36188576
http://dx.doi.org/10.3389/fphar.2022.958882