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XBP1-mediated activation of the STING signalling pathway in macrophages contributes to liver fibrosis progression

BACKGROUND & AIMS: XBP1 modulates the macrophage proinflammatory response, but its function in macrophage stimulator of interferon genes (STING) activation and liver fibrosis is unknown. X-box binding protein 1 (XBP1) has been shown to promote macrophage nucleotide-binding oligomerization domain...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Bu, Qingfa, Liu, Mu, Zhang, Rui, Gu, Jian, Li, Lei, Zhou, Jinren, Liang, Yuan, Su, Wantong, Liu, Zheng, Wang, Mingming, Lian, Zhexiong, Lu, Ling, Zhou, Haoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520276/
https://www.ncbi.nlm.nih.gov/pubmed/36185574
http://dx.doi.org/10.1016/j.jhepr.2022.100555