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XBP1-mediated activation of the STING signalling pathway in macrophages contributes to liver fibrosis progression
BACKGROUND & AIMS: XBP1 modulates the macrophage proinflammatory response, but its function in macrophage stimulator of interferon genes (STING) activation and liver fibrosis is unknown. X-box binding protein 1 (XBP1) has been shown to promote macrophage nucleotide-binding oligomerization domain...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520276/ https://www.ncbi.nlm.nih.gov/pubmed/36185574 http://dx.doi.org/10.1016/j.jhepr.2022.100555 |