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Vitamin C modulates the levels of several proteins of the mitochondrial complex III and its activity in the mouse liver

Ascorbate is a crucial antioxidant and essential cofactor of biosynthetic and regulatory enzymes. Unlike humans, mice can synthesize ascorbate thanks to the key enzyme gulonolactone oxidase (Gulo). In the present study, we used the Gulo(−/−) mouse model, which cannot synthesize their own ascorbate t...

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Detalles Bibliográficos
Autores principales: Aumailley, Lucie, Bourassa, Sylvie, Gotti, Clarisse, Droit, Arnaud, Lebel, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520280/
https://www.ncbi.nlm.nih.gov/pubmed/36179436
http://dx.doi.org/10.1016/j.redox.2022.102491