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Impact of Sacubitril/Valsartan on surfactant binding proteins, central sleep apneas, lung function tests and heart failure biomarkers: Hemodynamic or pleiotropism?

PURPOSE: Little is known about the mechanism underlying Sacubitril/Valsartan effects in patients with heart failure (HFrEF). Aim of the study is to assess hemodynamic vs. non-hemodynamic Sacubitril/Valsartan effects by analyzing several biological and functional parameters. METHODS: Seventy-nine pat...

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Detalles Bibliográficos
Autores principales: Mapelli, Massimo, Mattavelli, Irene, Salvioni, Elisabetta, Banfi, Cristina, Ghilardi, Stefania, De Martino, Fabiana, Gugliandolo, Paola, Mantegazza, Valentina, Volpato, Valentina, Basile, Christian, Branco Pires, Maria Inês Fiuza, Sassi, Valentina, Nusca, Benedetta, Vignati, Carlo, Contini, Mauro, Sforza, Chiarella, Biondi, Maria Luisa, Perrone Filardi, Pasquale, Agostoni, Piergiuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520298/
https://www.ncbi.nlm.nih.gov/pubmed/36186983
http://dx.doi.org/10.3389/fcvm.2022.971108