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Bcl-xL activity influences outcome of the mitotic arrest

Microtubule-targeting (MT) drugs taxanes and vinca alkaloids are widely used as chemotherapeutic agents against different tumors for more than 30 years because of their ability to block mitotic progression by disrupting the mitotic spindle and activating the spindle assembly checkpoint (SAC) for a p...

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Detalles Bibliográficos
Autores principales: Suleimenov, M., Bekbayev, S., Ten, M., Suleimenova, N., Tlegenova, M., Nurmagambetova, A., Kauanova, S., Vorobjev, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520339/
https://www.ncbi.nlm.nih.gov/pubmed/36188556
http://dx.doi.org/10.3389/fphar.2022.933112