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Acute and inherited piRNA-mediated silencing in a rde-3 ribonucleotidyltransferase mutant

We recently developed a piRNA-based silencing assay (piRNAi) to study small-RNA mediated epigenetic silencing: acute gene silencing is induced by synthetic piRNAs expressed from extra-chromosomal array and transgenerational inheritance can be quantified after array loss. The assay allows inheritance...

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Detalles Bibliográficos
Autores principales: Priyadarshini, Monika, AlHarbi, Sarah, Frøkjær-Jensen, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520340/
https://www.ncbi.nlm.nih.gov/pubmed/36188099
http://dx.doi.org/10.17912/micropub.biology.000638