A combined analysis of bulk and single-cell sequencing data reveals that depleted extracellular matrix and enhanced immune processes co-contribute to fluorouracil beneficial responses in gastric cancer

Fluorouracil, also known as 5-FU, is one of the most commonly used chemotherapy drugs in the treatment of advanced gastric cancer (GC). Whereas, the presence of innate or acquired resistance largely limits its survival benefit in GC patients. Although accumulated studies have demonstrated the involv...

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Detalles Bibliográficos
Autores principales: Dong, Shaowei, Zhang, Siyu, Zhao, Pan, Lin, Guanchuan, Ma, Xiaoshi, Xu, Jing, Zhang, Hao, Hu, Jiliang, Zou, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520597/
https://www.ncbi.nlm.nih.gov/pubmed/36189263
http://dx.doi.org/10.3389/fimmu.2022.999551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520597/
https://www.ncbi.nlm.nih.gov/pubmed/36189263
http://dx.doi.org/10.3389/fimmu.2022.999551

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