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A novel automated morphological analysis of Iba1+ microglia using a deep learning assisted model

There is growing evidence for the key role of microglial functional state in brain pathophysiology. Consequently, there is a need for efficient automated methods to measure the morphological changes distinctive of microglia functional states in research settings. Currently, many commonly used automa...

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Detalles Bibliográficos
Autores principales: Stetzik, Lucas, Mercado, Gabriela, Smith, Lindsey, George, Sonia, Quansah, Emmanuel, Luda, Katarzyna, Schulz, Emily, Meyerdirk, Lindsay, Lindquist, Allison, Bergsma, Alexis, Jones, Russell G., Brundin, Lena, Henderson, Michael X., Pospisilik, John Andrew, Brundin, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520629/
https://www.ncbi.nlm.nih.gov/pubmed/36187297
http://dx.doi.org/10.3389/fncel.2022.944875