Cargando…

Chaperonin containing TCP-1 (CCT/TRiC) is a novel therapeutic and diagnostic target for neuroblastoma

Chaperonin containing TCP1 (CCT/TRiC) is a multi-subunit protein folding complex that enables the cancer phenotype to emerge from the mutational landscape that drives oncogenesis. We and others linked increased expression of CCT subunits to advanced tumor stage and invasiveness that inversely correl...

Descripción completa

Detalles Bibliográficos
Autores principales: Cox, Amanda, Nierenberg, Daniel, Camargo, Oscar, Lee, Eunkyung, Khaled, Amr S., Mazar, Joseph, Boohaker, Rebecca J., Westmoreland, Tamarah J., Khaled, Annette R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520665/
https://www.ncbi.nlm.nih.gov/pubmed/36185250
http://dx.doi.org/10.3389/fonc.2022.975088