Modification of Fab Fragments by Dibromopyridazinediones Carrying Mono- and Double-Biotin Functionalities

[Image: see text] To verify the potencies of dibromopyridazinediones with mono- and double-biotin groups, the functions as cysteine-selective biotinylation reagents were evaluated through conjugation with a goat anti-mouse IgG Fab fragment as a functional protein model. The starting Fab was reduced...

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Detalles Bibliográficos
Autores principales: Matsushita, Takahiko, Maruyama, Naoto, Koyama, Tetsuo, Hatano, Ken, Matsuoka, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520716/
https://www.ncbi.nlm.nih.gov/pubmed/36188280
http://dx.doi.org/10.1021/acsomega.2c04379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520716/
https://www.ncbi.nlm.nih.gov/pubmed/36188280
http://dx.doi.org/10.1021/acsomega.2c04379

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