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Modification of Fab Fragments by Dibromopyridazinediones Carrying Mono- and Double-Biotin Functionalities
[Image: see text] To verify the potencies of dibromopyridazinediones with mono- and double-biotin groups, the functions as cysteine-selective biotinylation reagents were evaluated through conjugation with a goat anti-mouse IgG Fab fragment as a functional protein model. The starting Fab was reduced...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520716/ https://www.ncbi.nlm.nih.gov/pubmed/36188280 http://dx.doi.org/10.1021/acsomega.2c04379 |