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Poor prognosis, hypomethylation, and immune infiltrates are associated with downregulation of INMT in head and neck squamous cell carcinoma

Background: Indiolethylamine-N-methyltransferase (INMT) is a methyltransferase responsible for transferring methyl groups from methyl donor SAM to its substrate. S-adenosyl-l-methionine (SAM), obtained from the methionine cycle, is a naturally occurring sulfonium compound that is vital to cellular m...

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Detalles Bibliográficos
Autores principales: Cui, Kun, Yao, Xi, Wei, Zhengbo, yang, Yujia, Liu, Xinli, Huang, Zhongheng, Huo, Huimin, Tang, Jinping, Xie, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520724/
https://www.ncbi.nlm.nih.gov/pubmed/36186458
http://dx.doi.org/10.3389/fgene.2022.917344