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Human fetal skin derived merkel cells display distinctive characteristics in vitro and in bio-engineered skin substitutes in vivo

Human skin contains specialized neuroendocrine Merkel cells responsible for fine touch sensation. In the present study, we performed in-depth analysis of Merkel cells in human fetal back skin. We revealed that these Merkel cells expressed cytokeratin 20 (CK20), were positive for the neuroendocrine m...

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Detalles Bibliográficos
Autores principales: Michalak-Micka, Katarzyna, Rütsche, Dominic, Mazzone, Luca, Büchler, Vanessa L., Moehrlen, Ueli, Klar, Agnes S., Biedermann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520781/
https://www.ncbi.nlm.nih.gov/pubmed/36185452
http://dx.doi.org/10.3389/fbioe.2022.983870