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Identifying genes associated with brain volumetric differences through tissue specific transcriptomic inference from GWAS summary data

BACKGROUND: Brain volume has been widely studied in the neuroimaging field, since it is an important and heritable trait associated with brain development, aging and various neurological and psychiatric disorders. Genome-wide association studies (GWAS) have successfully identified numerous associati...

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Detalles Bibliográficos
Autores principales: Mai, Hung, Bao, Jingxuan, Thompson, Paul M., Kim, Dokyoon, Shen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520794/
https://www.ncbi.nlm.nih.gov/pubmed/36171548
http://dx.doi.org/10.1186/s12859-022-04947-w