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Interpretation of the role of germline and somatic non-coding mutations in cancer: expression and chromatin conformation informed analysis
BACKGROUND: There has been extensive scrutiny of cancer driving mutations within the exome (especially amino acid altering mutations) as these are more likely to have a clear impact on protein functions, and thus on cell biology. However, this has come at the neglect of systematic identification of...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520844/ https://www.ncbi.nlm.nih.gov/pubmed/36171609 http://dx.doi.org/10.1186/s13148-022-01342-3 |