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β-Hydroxyphosphocarnitine modifies fibrosis, steatosis and improves liver function in non-alcoholic steatohepatitis induced in rats

BACKGROUND: Non-alcoholic steatohepatitis (NASH) is a chronic disease characterized by inflammation, steatosis, and liver fibrosis. The liver is particularly affected by alterations in lipid metabolism. Our aim was to evaluate the effect of β-hydroxyphosphocarnitine (β-HPC) on NASH induced in rats....

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Detalles Bibliográficos
Autores principales: Sánchez-Quevedo, Janet, Ocampo-Rodríguez, Emmanuel, Alvarez-Ayala, Elizabeth, Rodríguez-López, Anahí, Duarte-Vázquez, Miguel Angel, Rosado, Jorge Luis, Rodríguez-Fragoso, Lourdes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520892/
https://www.ncbi.nlm.nih.gov/pubmed/36175992
http://dx.doi.org/10.1186/s40360-022-00613-2