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Transcriptional signatures of the BCL2 family for individualized acute myeloid leukaemia treatment

BACKGROUND: Although anti-apoptotic proteins of the B-cell lymphoma-2 (BCL2) family have been utilized as therapeutic targets in acute myeloid leukaemia (AML), their complicated regulatory networks make individualized therapy difficult. This study aimed to discover the transcriptional signatures of...

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Detalles Bibliográficos
Autores principales: Lee, Chansub, Lee, Sungyoung, Park, Eunchae, Hong, Junshik, Shin, Dong-Yeop, Byun, Ja Min, Yun, Hongseok, Koh, Youngil, Yoon, Sung-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520894/
https://www.ncbi.nlm.nih.gov/pubmed/36171613
http://dx.doi.org/10.1186/s13073-022-01115-w