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Transcriptional signatures of the BCL2 family for individualized acute myeloid leukaemia treatment
BACKGROUND: Although anti-apoptotic proteins of the B-cell lymphoma-2 (BCL2) family have been utilized as therapeutic targets in acute myeloid leukaemia (AML), their complicated regulatory networks make individualized therapy difficult. This study aimed to discover the transcriptional signatures of...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520894/ https://www.ncbi.nlm.nih.gov/pubmed/36171613 http://dx.doi.org/10.1186/s13073-022-01115-w |