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Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

BACKGROUND: Cellular immune responses are phenotypically and functionally perturbed during HIV-1 infection, with the majority of function restored upon antiretroviral therapy (ART). Despite ART, residual inflammation remains that can lead to HIV-related co-morbidities and mortality, indicating that...

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Detalles Bibliográficos
Autores principales: Pollara, Justin, Khanal, Santosh, Edwards, R. Whitney, Hora, Bhavna, Ferrari, Guido, Haynes, Barton F., Bradley, Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520965/
https://www.ncbi.nlm.nih.gov/pubmed/36175869
http://dx.doi.org/10.1186/s12865-022-00523-2