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PtdIns(3,4)P(2), Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages

Phosphoinositides are pivotal regulators of vesicular traffic and signaling during phagocytosis. Phagosome formation, the initial step of the process, is characterized by local membrane remodeling and reorganization of the actin cytoskeleton that leads to formation of the pseudopods that drive parti...

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Detalles Bibliográficos
Autores principales: Montaño-Rendón, Fernando, Walpole, Glenn F.W., Krause, Matthias, Hammond, Gerald R.V., Grinstein, Sergio, Fairn, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521245/
https://www.ncbi.nlm.nih.gov/pubmed/36165850
http://dx.doi.org/10.1083/jcb.202207042