Cargando…

PtdIns(3,4)P(2), Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages

Phosphoinositides are pivotal regulators of vesicular traffic and signaling during phagocytosis. Phagosome formation, the initial step of the process, is characterized by local membrane remodeling and reorganization of the actin cytoskeleton that leads to formation of the pseudopods that drive parti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Montaño-Rendón, Fernando, Walpole, Glenn F.W., Krause, Matthias, Hammond, Gerald R.V., Grinstein, Sergio, Fairn, Gregory D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521245/ https://www.ncbi.nlm.nih.gov/pubmed/36165850 http://dx.doi.org/10.1083/jcb.202207042

Ejemplares similares

Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2)
por: Hammond, Gerald R. V., et al.
Publicado: (2009)

Novel PtdIns(3)P-binding protein Etf1 functions as an effector of the Vps34 PtdIns 3-kinase in autophagy
por: Wurmser, Andrew E., et al.
Publicado: (2002)

Probing PtdIns4P’s localization
por: Short, Ben
Publicado: (2014)

PtdIns4KIIα generates endosomal PtdIns(4)P and is required for receptor sorting at early endosomes
por: Henmi, Yuji, et al.
Publicado: (2016)

PtdIns(4,5)P(2) and PtdIns3P coordinate to regulate phagosomal sealing for apoptotic cell clearance
por: Cheng, Shiya, et al.
Publicado: (2015)

Phagosomal membrane targeting of Irgm1 via PtdIns(3,4)P(2) and PtdIns(3,4,5)P(3) promotes mycobacterial immunity
por: Tiwari, Sangeeta, et al.
Publicado: (2009)

PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking
por: Wood, Christopher S., et al.
Publicado: (2009)

Hippocampal neurons maintain a large PtdIns(4)P pool that results in faster PtdIns(4,5)P(2) synthesis
por: de la Cruz, Lizbeth, et al.
Publicado: (2022)

RDGBα, a PtdIns-PtdOH transfer protein, regulates G-protein-coupled PtdIns(4,5)P(2) signalling during Drosophila phototransduction
por: Yadav, Shweta, et al.
Publicado: (2015)

PtdIns 3-Kinase Orchestrates Autophagosome Formation in Yeast
por: Obara, Keisuke, et al.
Publicado: (2011)

Inositol Polyphosphate-4-Phosphatase Type I Negatively Regulates Phagocytosis via Dephosphorylation of Phagosomal PtdIns(3,4)P(2)
por: Nigorikawa, Kiyomi, et al.
Publicado: (2015)

pH of endophagosomes controls association of their membranes with Vps34 and PtdIns(3)P levels
por: Naufer, Amriya, et al.
Publicado: (2018)

Lysophosphatidylinositol-Acyltransferase-1 (LPIAT1) Is Required to Maintain Physiological Levels of PtdIns and PtdInsP(2) in the Mouse
por: Anderson, Karen E., et al.
Publicado: (2013)

PtdIns(4,5)P2 and PtdIns(3,4,5)P3 dynamics during focal adhesions assembly and disassembly in a cancer cell line
por: ALFAHAD, Dhurgham, et al.
Publicado: (2020)

Link the channel activity to PtdIns(4,5)P(2) dynamics
por: Mori, Masayuki X
Publicado: (2014)

Lamellipodin promotes actin assembly by clustering Ena/VASP proteins and tethering them to actin filaments
por: Hansen, Scott D, et al.
Publicado: (2015)

A protein complex that regulates PtdIns(3,5)P(2) levels
por: Michell, Robert H, et al.
Publicado: (2009)

SAC1 degrades its lipid substrate PtdIns4P in the endoplasmic reticulum to maintain a steep chemical gradient with donor membranes
por: Zewe, James P, et al.
Publicado: (2018)

Enforced expression of phosphatidylinositol 4-phosphate 5-kinase homolog alters PtdIns(4,5)P(2) distribution and the localization of small G-proteins
por: Yang, Yanbo, et al.
Publicado: (2019)

PtdIns(4,5)P(2) turnover is required for multiple stages during clathrin- and actin-dependent endocytic internalization
por: Sun, Yidi, et al.
Publicado: (2007)

New insights into the functions of PtdIns(3,5)P(2) in the pathogenisis of neurodegenerative disorders
por: Tsuruta, Fuminori
Publicado: (2016)

PtdIns3P controls mTORC1 signaling through lysosomal positioning
por: Hong, Zhi, et al.
Publicado: (2017)

IPIP27 Coordinates PtdIns(4,5)P(2) Homeostasis for Successful Cytokinesis
por: Carim, Sabrya C., et al.
Publicado: (2019)

Apilimod, a candidate anticancer therapeutic, arrests not only PtdIns(3,5)P(2) but also PtdIns5P synthesis by PIKfyve and induces bafilomycin A1-reversible aberrant endomembrane dilation
por: Sbrissa, Diego, et al.
Publicado: (2018)

Alteration of Epithelial Structure and Function Associated with PtdIns(4,5)P(2) Degradation by a Bacterial Phosphatase
por: Mason, David, et al.
Publicado: (2007)

Initiation and disassembly of filopodia tip complexes containing VASP and lamellipodin
por: Cheng, Karen W., et al.
Publicado: (2020)

Three sorting nexins drive the degradation of apoptotic cells in response to PtdIns(3)P signaling
por: Lu, Nan, et al.
Publicado: (2011)

PtdIns (3,4,5) P3 Recruitment of Myo10 Is Essential for Axon Development
por: Yu, Huali, et al.
Publicado: (2012)

The PtdIns3‐phosphatase MTMR3 interacts with mTORC1 and suppresses its activity
por: Hao, Feike, et al.
Publicado: (2016)

PtdIns4P-mediated electrostatic forces influence S-acylation of peripheral proteins at the Golgi complex
por: Chumpen Ramirez, Sabrina, et al.
Publicado: (2020)

PTEN and Other PtdIns(3,4,5)P(3) Lipid Phosphatases in Breast Cancer
por: Csolle, Mariah P., et al.
Publicado: (2020)

PtdIns4P on Dispersed Trans-Golgi Network Mediates NLRP3 Inflammasome Activation
por: Chen, Jueqi, et al.
Publicado: (2018)

Omegasome-proximal PtdIns(4,5)P(2) couples F-actin mediated mitoaggregate disassembly with autophagosome formation during mitophagy
por: Hsieh, Cheng-Wei, et al.
Publicado: (2019)

c-Abl, Lamellipodin, and Ena/VASP Proteins Cooperate in Dorsal Ruffling of Fibroblasts and Axonal Morphogenesis
por: Michael, Magdalene, et al.
Publicado: (2010)

PtdIns(3,4,5)P(3)-Dependent and -Independent Roles for PTEN in the Control of Cell Migration
por: Leslie, Nick R., et al.
Publicado: (2007)

Phospholipase Cζ binding to PtdIns(4,5)P(2) requires the XY-linker region
por: Nomikos, Michail, et al.
Publicado: (2011)

The PtdIns 3-Kinase/Akt Pathway Regulates Macrophage-Mediated ADCC against B Cell Lymphoma
por: Joshi, Trupti, et al.
Publicado: (2009)

A novel mass assay to quantify the bioactive lipid PtdIns3P in various biological samples
por: Chicanne, Gaëtan, et al.
Publicado: (2012)

Investigation of the PtdIns(4,5)P(2 )dependence of plasma membrane receptor endocytosis in living cells
por: Tóth, Dániel, et al.
Publicado: (2009)

Legionella-Containing Vacuoles Capture PtdIns(4)P-Rich Vesicles Derived from the Golgi Apparatus
por: Weber, Stephen, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_9und1n1iibevbast4gthkc99qm