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Regulation of Pdx1 by oxidative stress and Nrf2 in pancreatic beta-cells
The beta-cell identity gene, pancreatic duodenal homeobox 1 (Pdx1), plays critical roles in many aspects of the life of beta-cells including differentiation, maturation, function, survival and proliferation. High levels of reactive oxygen species (ROS) are extremely toxic to cells and especially to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521308/ https://www.ncbi.nlm.nih.gov/pubmed/36187092 http://dx.doi.org/10.3389/fendo.2022.1011187 |