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Prediction value of the genetic risk of type 2 diabetes on the amnestic mild cognitive impairment conversion to Alzheimer’s disease

Amnestic mild cognitive impairment (aMCI) and Type 2 diabetes mellitus (T2DM) are both important risk factors for Alzheimer’s disease (AD). We aimed to investigate whether a T2DM-specific polygenic risk score (PRS(sT2DM)) can predict the conversion of aMCI to AD and further explore the underlying ne...

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Detalles Bibliográficos
Autores principales: Yang, Jiayang, Wang, Zirui, Fu, Yumeng, Xu, Jiayuan, Zhang, Yang, Qin, Wen, Zhang, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521369/
https://www.ncbi.nlm.nih.gov/pubmed/36185474
http://dx.doi.org/10.3389/fnagi.2022.964463