Cargando…

Engineered myoglobin as a catalyst for atom transfer radical cyclisation

Myoglobin was subjected to site-directed mutagenesis and transformed into a catalyst able to perform atom transfer radical cyclisation reactions, i.e. intramolecular atom transfer radical additions. Replacing the iron-coordinating histidine with serine, or introducing small changes inside or at the...

Descripción completa

Detalles Bibliográficos
Autores principales: Lubskyy, Andriy, Guo, Chao, Chadwick, Robert J., Petri-Fink, Alke, Bruns, Nico, Pellizzoni, Michela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521412/
https://www.ncbi.nlm.nih.gov/pubmed/36093761
http://dx.doi.org/10.1039/d2cc03227a