Comprehensive CRISPR-Cas9 screen identifies factors which are important for plasmablast development

Plasma cells (PCs) and their progenitors plasmablasts (PBs) are essential for the acute and long-term protection of the host against infections by providing vast levels of highly specific antibodies. Several transcription factors, like Blimp1 and Irf4, are already known to be essential for PC and PB...

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Detalles Bibliográficos
Autores principales: Pinter, Theresa, Fischer, Maria, Schäfer, Markus, Fellner, Michaela, Jude, Julian, Zuber, Johannes, Busslinger, Meinrad, Wöhner, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521597/
https://www.ncbi.nlm.nih.gov/pubmed/36189249
http://dx.doi.org/10.3389/fimmu.2022.979606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521597/
https://www.ncbi.nlm.nih.gov/pubmed/36189249
http://dx.doi.org/10.3389/fimmu.2022.979606

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