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A scalable system for the fast production of RNA with homogeneous terminal ends

In vitro transcription (IVT) using T7 RNA polymerase has become the most common method to synthesize RNAs for use in basic research and pharmaceutical applications. To solve the heterogeneity issue associated with the system, cis-acting ribozymes have been exploited to direct co-transcriptional proc...

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Detalles Bibliográficos
Autores principales: Chen, Yuchen, Cheng, Yan, Lin, Jinzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521606/
https://www.ncbi.nlm.nih.gov/pubmed/36121187
http://dx.doi.org/10.1080/15476286.2022.2123640