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Perspective on Dentoalveolar Manifestations Resulting From PHOSPHO1 Loss-of-Function: A Form of Pseudohypophosphatasia?

Mineralization of the skeleton occurs by several physicochemical and biochemical processes and mechanisms that facilitate the deposition of hydroxyapatite (HA) in specific areas of the extracellular matrix (ECM). Two key phosphatases, phosphatase, orphan 1 (PHOSPHO1) and tissue-non-specific alkaline...

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Detalles Bibliográficos
Autores principales: Mohamed, Fatma F., Chavez, Michael B., de Oliveira, Flavia Amadeu, Narisawa, Sonoko, Farquharson, Colin, Millán, José Luis, Foster, Brian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521815/
https://www.ncbi.nlm.nih.gov/pubmed/36185572
http://dx.doi.org/10.3389/fdmed.2022.826387