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On the incongruence of genotype-phenotype and fitness landscapes
The mapping from genotype to phenotype to fitness typically involves multiple nonlinearities that can transform the effects of mutations. For example, mutations may contribute additively to a phenotype, but their effects on fitness may combine non-additively because selection favors a low or interme...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521842/ https://www.ncbi.nlm.nih.gov/pubmed/36121840 http://dx.doi.org/10.1371/journal.pcbi.1010524 |