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A novel quantitative computer-assisted drug-induced liver injury causality assessment tool (DILI-CAT)

BACKGROUND AND AIMS: We hypothesized that a drug’s clinical signature (or phenotype) of liver injury can be assessed and used to quantitatively develop a computer-assisted DILI causality assessment-tool (DILI-CAT). Therefore, we evaluated drug-specific DILI-phenotypes for amoxicillin-clavulanate (AM...

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Detalles Bibliográficos
Autores principales: Tillmann, Hans L., Suzuki, Ayako, Merz, Michael, Hermann, Richard, Rockey, Don C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521919/
https://www.ncbi.nlm.nih.gov/pubmed/36174069
http://dx.doi.org/10.1371/journal.pone.0271304