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Prognostic significance of the urokinase plasminogen activator system in tissue and serum of dogs with appendicular osteosarcoma

Urokinase plasminogen activator (uPA) and its receptor uPAR promote cancer invasion and metastasis and are emerging therapeutic targets in both human and canine malignancies. While their clinical significance is well-characterized in multiple human tumor types, studies investigating their roles in o...

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Detalles Bibliográficos
Autores principales: Matsuyama, Arata, Wood, Geoffrey A., Speare, Rachael, Schott, Courtney R., Mutsaers, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522282/
https://www.ncbi.nlm.nih.gov/pubmed/36174075
http://dx.doi.org/10.1371/journal.pone.0273811