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Aging-regulated TUG1 is dispensable for endothelial cell function

The evolutionary conserved Taurine Upregulated Gene 1 (TUG1) is a ubiquitously expressed gene that is one of the highest expressed genes in human and rodent endothelial cells (ECs). We here show that TUG1 expression decreases significantly in aging mouse carotid artery ECs and human ECs in vitro, in...

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Detalles Bibliográficos
Autores principales: Gimbel, Anna Theresa, Koziarek, Susanne, Theodorou, Kosta, Schulz, Jana Felicitas, Stanicek, Laura, Kremer, Veerle, Ali, Tamer, Günther, Stefan, Kumar, Sandeep, Jo, Hanjoong, Hübner, Norbert, Maegdefessel, Lars, Dimmeler, Stefanie, van Heesch, Sebastiaan, Boon, Reinier A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522302/
https://www.ncbi.nlm.nih.gov/pubmed/36173935
http://dx.doi.org/10.1371/journal.pone.0265160