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Using the HepaCometChip Assay for Broad‐Spectrum DNA Damage Analysis

Exposure to DNA damaging agents can lead to mutations that cause cancer. The liver is particularly vulnerable because it contains high levels of Cytochrome P450 enzymes that can convert xenobiotics into DNA reactive metabolites that form potentially carcinogenic bulky DNA adducts. As such, current r...

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Detalles Bibliográficos
Autores principales: Owiti, Norah A., Kaushal, Simran, Martin, Lincoln, Sly, Jamie, Swartz, Carol D., Fowler, Jasmine, Corrigan, Joshua J., Recio, Les, Engelward, Bevin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522315/
https://www.ncbi.nlm.nih.gov/pubmed/36165707
http://dx.doi.org/10.1002/cpz1.563