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A quantile integral linear model to quantify genetic effects on phenotypic variability

Detecting genetic variants associated with the variance of complex traits, that is, variance quantitative trait loci (vQTLs), can provide crucial insights into the interplay between genes and environments and how they jointly shape human phenotypes in the population. We propose a quantile integral l...

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Detalles Bibliográficos
Autores principales: Miao, Jiacheng, Lin, Yupei, Wu, Yuchang, Zheng, Boyan, Schmitz, Lauren L., Fletcher, Jason M., Lu, Qiongshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522331/
https://www.ncbi.nlm.nih.gov/pubmed/36122202
http://dx.doi.org/10.1073/pnas.2212959119