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A quantile integral linear model to quantify genetic effects on phenotypic variability
Detecting genetic variants associated with the variance of complex traits, that is, variance quantitative trait loci (vQTLs), can provide crucial insights into the interplay between genes and environments and how they jointly shape human phenotypes in the population. We propose a quantile integral l...
Autores principales: | Miao, Jiacheng, Lin, Yupei, Wu, Yuchang, Zheng, Boyan, Schmitz, Lauren L., Fletcher, Jason M., Lu, Qiongshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522331/ https://www.ncbi.nlm.nih.gov/pubmed/36122202 http://dx.doi.org/10.1073/pnas.2212959119 |
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