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Functional determination of calcium-binding sites required for the activation of inositol 1,4,5-trisphosphate receptors
Inositol 1,4,5-trisphosphate receptors (IP(3)Rs) initiate a diverse array of physiological responses by carefully orchestrating intracellular calcium (Ca(2+)) signals in response to various external cues. Notably, IP(3)R channel activity is determined by several obligatory factors, including IP(3),...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522344/ https://www.ncbi.nlm.nih.gov/pubmed/36122240 http://dx.doi.org/10.1073/pnas.2209267119 |