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Functional determination of calcium-binding sites required for the activation of inositol 1,4,5-trisphosphate receptors

Inositol 1,4,5-trisphosphate receptors (IP(3)Rs) initiate a diverse array of physiological responses by carefully orchestrating intracellular calcium (Ca(2+)) signals in response to various external cues. Notably, IP(3)R channel activity is determined by several obligatory factors, including IP(3),...

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Detalles Bibliográficos
Autores principales: Arige, Vikas, Terry, Lara E., Wagner, Larry E., Malik, Sundeep, Baker, Mariah R., Fan, Guizhen, Joseph, Suresh K., Serysheva, Irina I., Yule, David I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522344/
https://www.ncbi.nlm.nih.gov/pubmed/36122240
http://dx.doi.org/10.1073/pnas.2209267119

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