The alternative lengthening of telomeres mechanism jeopardizes telomere integrity if not properly restricted

A substantial number of human cancers are telomerase-negative and elongate physiologically damaged telomeres through a break-induced replication (BIR)-based mechanism known as alternative lengthening of telomeres (ALT). We recently demonstrated that inhibiting the transcription of the telomeric long...

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Detalles Bibliográficos
Autores principales: Silva, Bruno, Arora, Rajika, Azzalin, Claus M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522348/
https://www.ncbi.nlm.nih.gov/pubmed/36122232
http://dx.doi.org/10.1073/pnas.2208669119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522348/
https://www.ncbi.nlm.nih.gov/pubmed/36122232
http://dx.doi.org/10.1073/pnas.2208669119

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