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A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamsters

The high transmissibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a primary driver of the COVID-19 pandemic. While existing interventions prevent severe disease, they exhibit mixed efficacy in preventing transmission, presumably due to their limited antiviral effects in th...

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Detalles Bibliográficos
Autores principales: Chaturvedi, Sonali, Beutler, Nathan, Vasen, Gustavo, Pablo, Michael, Chen, Xinyue, Calia, Giuliana, Buie, Lauren, Rodick, Robert, Smith, Davey, Rogers, Thomas, Weinberger, Leor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522362/
https://www.ncbi.nlm.nih.gov/pubmed/36074824
http://dx.doi.org/10.1073/pnas.2204624119