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A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamsters
The high transmissibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a primary driver of the COVID-19 pandemic. While existing interventions prevent severe disease, they exhibit mixed efficacy in preventing transmission, presumably due to their limited antiviral effects in th...
Autores principales: | Chaturvedi, Sonali, Beutler, Nathan, Vasen, Gustavo, Pablo, Michael, Chen, Xinyue, Calia, Giuliana, Buie, Lauren, Rodick, Robert, Smith, Davey, Rogers, Thomas, Weinberger, Leor S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522362/ https://www.ncbi.nlm.nih.gov/pubmed/36074824 http://dx.doi.org/10.1073/pnas.2204624119 |
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