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Sphingosine kinases regulate ER contacts with late endocytic organelles and cholesterol trafficking

Membrane contact sites (MCS), close membrane apposition between organelles, are platforms for interorganellar transfer of lipids including cholesterol, regulation of lipid homeostasis, and co-ordination of endocytic trafficking. Sphingosine kinases (SphKs), two isoenzymes that phosphorylate sphingos...

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Detalles Bibliográficos
Autores principales: Palladino, Elisa N. D., Bernas, Tytus, Green, Christopher D., Weigel, Cynthia, Singh, Sandeep K., Senkal, Can E., Martello, Andrea, Kennelly, John P., Bieberich, Erhard, Tontonoz, Peter, Ford, David A., Milstien, Sheldon, Eden, Emily R., Spiegel, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522378/
https://www.ncbi.nlm.nih.gov/pubmed/36122218
http://dx.doi.org/10.1073/pnas.2204396119