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Sphingosine kinases regulate ER contacts with late endocytic organelles and cholesterol trafficking
Membrane contact sites (MCS), close membrane apposition between organelles, are platforms for interorganellar transfer of lipids including cholesterol, regulation of lipid homeostasis, and co-ordination of endocytic trafficking. Sphingosine kinases (SphKs), two isoenzymes that phosphorylate sphingos...
Autores principales: | Palladino, Elisa N. D., Bernas, Tytus, Green, Christopher D., Weigel, Cynthia, Singh, Sandeep K., Senkal, Can E., Martello, Andrea, Kennelly, John P., Bieberich, Erhard, Tontonoz, Peter, Ford, David A., Milstien, Sheldon, Eden, Emily R., Spiegel, Sarah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522378/ https://www.ncbi.nlm.nih.gov/pubmed/36122218 http://dx.doi.org/10.1073/pnas.2204396119 |
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