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Scavenger receptor-targeted plaque delivery of microRNA-coated nanoparticles for alleviating atherosclerosis

Atherosclerosis treatments by gene regulation are garnering attention, yet delivery of gene cargoes to atherosclerotic plaques remains inefficient. Here, we demonstrate that assembly of therapeutic oligonucleotides into a three-dimensional spherical nucleic acid nanostructure improves their systemic...

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Detalles Bibliográficos
Autores principales:	Bai, Qianqian, Xiao, Yu, Hong, Huiling, Cao, Xiaoyun, Zhang, Lei, Han, Ruifang, Lee, Leo Kit Cheung, Xue, Evelyn Y., Tian, Xiao Yu, Choi, Chung Hang Jonathan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522431/ https://www.ncbi.nlm.nih.gov/pubmed/36122215 http://dx.doi.org/10.1073/pnas.2201443119

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