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Phase II study of sodium valproate in combination with oral etoposide in platinum-resistant ovarian cancer
Patients with platinum-resistant ovarian cancer (PROC) have limited therapeutic options and poor survival. There is a need for the development of newer therapies. Sodium valproic acid (VPA) is a short-chain fatty acid histone deacetylase (HDAC) inhibitor with antitumor activity in preclinical models...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522437/ https://www.ncbi.nlm.nih.gov/pubmed/36175588 http://dx.doi.org/10.1007/s12032-022-01833-6 |