Investigation of MicroRNA-134 as a Target against Seizures and SUDEP in a Mouse Model of Dravet Syndrome

Dravet syndrome (DS) is a catastrophic form of pediatric epilepsy mainly caused by noninherited mutations in the SCN1A gene. DS patients suffer severe and life-threatening focal and generalized seizures which are often refractory to available anti-seizure medication. Antisense oligonucleotides (ASOs...

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Detalles Bibliográficos
Autores principales: Gerbatin, Rogério R., Augusto, Joana, Morris, Gareth, Campbell, Aoife, Worm, Jesper, Langa, Elena, Reschke, Cristina R., Henshall, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Research Article: Negative Results
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522462/
https://www.ncbi.nlm.nih.gov/pubmed/36240080
http://dx.doi.org/10.1523/ENEURO.0112-22.2022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522462/
https://www.ncbi.nlm.nih.gov/pubmed/36240080
http://dx.doi.org/10.1523/ENEURO.0112-22.2022

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