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In-silico drug trials for precision medicine in atrial fibrillation: From ionic mechanisms to electrocardiogram-based predictions in structurally-healthy human atria

Atrial fibrillation (AF) inducibility, sustainability and response to pharmacological treatment of individual patients are expected to be determined by their ionic current properties, especially in structurally-healthy atria. Mechanisms underlying AF and optimal cardioversion are however still uncle...

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Detalles Bibliográficos
Autores principales: Dasí, Albert, Roy, Aditi, Sachetto, Rafael, Camps, Julia, Bueno-Orovio, Alfonso, Rodriguez, Blanca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522526/
https://www.ncbi.nlm.nih.gov/pubmed/36187798
http://dx.doi.org/10.3389/fphys.2022.966046