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Loss of AID exacerbates the malignant progression of CLL

Activation-induced cytidine deaminase (AID) has been implicated as both a positive and a negative factor in the progression of B cell chronic lymphocytic leukemia (CLL), but the role that it plays in the development and progression of this disease is still unclear. We generated an AID knockout CLL m...

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Detalles Bibliográficos
Autores principales: Lee, Avery C., Pingali, Sai Ravi, Pinilla-Ibarz, Javier A., Atchison, Michael L., Koumenis, Constantinos, Argon, Yair, Thomas-Tikhonenko, Andrei, De Trez, Carl, Hu, Chih-Chi Andrew, Tang, Chih-Hang Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522595/
https://www.ncbi.nlm.nih.gov/pubmed/36042317
http://dx.doi.org/10.1038/s41375-022-01663-5