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A preclinical model of cutaneous melanoma based on reconstructed human epidermis

Malignant melanoma is among the tumor entities with the highest increase of incidence worldwide. To elucidate melanoma progression and develop new effective therapies, rodent models are commonly used. While these do not adequately reflect human physiology, two-dimensional cell cultures lack crucial...

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Detalles Bibliográficos
Autores principales: Leikeim, Anna, Wußmann, Maximiliane, Schmidt, Freia F., Neto, Nuno G. B., Benz, Franziska, Tiltmann, Kendra, Junger, Corinna, Monaghan, Michael G., Schilling, Bastian, Groeber-Becker, Florian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522649/
https://www.ncbi.nlm.nih.gov/pubmed/36175453
http://dx.doi.org/10.1038/s41598-022-19307-0