Interruption of aberrant chromatin looping is required for regenerating RB1 function and suppressing tumorigenesis

RB transcriptional corepressor 1 (RB1) is a critical regulatory gene in physiological and pathological processes. Genetic mutation is considered to be the main cause of RB1 inactivation. However, accumulating evidence has shown that not all RB1 dysfunction is triggered by gene mutations, and the add...

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Detalles Bibliográficos
Autores principales: Wen, Xuyang, Ding, Tianyi, Li, Fang, Fan, Jiayan, Fan, Xianqun, Jia, Renbing, Zhang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522773/
https://www.ncbi.nlm.nih.gov/pubmed/36175480
http://dx.doi.org/10.1038/s42003-022-04007-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522773/
https://www.ncbi.nlm.nih.gov/pubmed/36175480
http://dx.doi.org/10.1038/s42003-022-04007-2

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