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Ferric quinate (QPLEX) interacts with the major outer membrane protein (MOMP) of Campylobacter jejuni and enters through the porin channel into the periplasmic space

Ferric chelates like ferric tyrosinate (TYPLEX) and the closely related ferric quinate (QPLEX) are structural mimics of bacterial siderophores. TYPLEX has been trialled as a feed additive in farming of commercial broilers, reducing Campylobacter loads by 2–3 log(10) and leading to faster growth and...

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Detalles Bibliográficos
Autores principales: Okoye, Jennifer C., Bellamy-Carter, Jeddidiah, Oldham, Neil J., Oldfield, Neil J., Mahdavi, Jafar, Soultanas, Panos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522878/
https://www.ncbi.nlm.nih.gov/pubmed/36212543
http://dx.doi.org/10.1016/j.csbj.2022.09.032